Technologies
At the InfectoGnostics Research Campus Jena, innovative technologies for the rapid identification of infectious pathogens and their antimicrobial resistance (AMR) are being developed and brought to market maturity in collaboration with industry partners. This translation facilitates to make faster and more accurate diagnoses or improve therapeutic approaches. In this context AI methods are increasingly being used, e.g. to facilitate the analysis of large data sets (in spectroscopy), to analyze patterns in diagnostic tests or to improve analysis and prognosis models for infectious diseases.
To date, the following in-house developments have been used for infection research on campus (reference to external links of InfectoGnostics partners, some references/links may be available only in German):
BLINK AG platform concept for decentralized diagnostics
BLINK X technology platform for decentralized analytics (microfluidic-free digital PCR)
INTER-ARRAY by fzmb GmbH
Solutions for the development and validation of multiparameter tests
SARS-CoV-2 in wastewater
PCR-based workflow from Analytik Jena GmbH for the detection of SARS-CoV-2 in wastewater
nanozoo.cloud
nanozoo implements end-to-end workflows that automate data-intensive biology from sample to report. One of their first services was an open access platform from nanozoo GmbH for analyzing raw data from genome sequencing in the context of COVID-19.
biophotonics diagnostics
Technologies and services for the rapid identification and classification of substances and microbes
- Diagnostics and process analytics at a new level using artificial intelligence (RAMANMETRIX and RAMANBIOASSAY)
Dynamic42
The Dynamic42 organ-on-chip platform enables a deeper understanding of human cell biology in health and disease. It can help to expand preclinical datasets, validate targets, investigate molecular mechanisms and prioritize further development.
ConsensusPrime tool on GitHub
Open source bioinformatics tool "ConsensusPrime" - pipeline for the ideal design of consensus primers for PCR
What the Phage on GitHub
Open source scalable workflow for the identification and analysis of bacteriophage sequences
The JIPipe software enables the automated evaluation of image data
The JIPipe software was developed by the Leibniz-HKI and significantly simplifies the analysis of images generated in research. Users can create flowcharts according to their application requirements and thus carry out automatic image analyses using artificial intelligence without any programming knowledge.
qBA software (English)
Open source software for quantitative analysis of 3-dimensional data of bacterial biofilms
from confocal laser scanning microscopy
Integrated Biobank Jena (IBBJ)
Central biobank for the Medical Faculty of the University Hospital Jena, where InfectoGnostics samples are also stored